State University of New York at Buffalo (1983)
Professor, Clinical Psychology
Office Hours: Flexible, by appointment
Phone Number: (631) 632-7859
Web site for Stony Brook temperament study: http://www.psychology.sunysb.edu/sbutmntstudy/
Dr. Klein is interested in developmental psychopathology and adult psychopathology, particularly mood disorders in children, adolescents, and adults. His research explores the intergenerational transmission of depression; the roles of temperament and emotional reactivity, and early adversity in the development and course of mood disorders; the long-term course and continuity of mood disorders; the classification of mood disorders; comorbidity between depression and other disorders; and the psychotherapeutic and psychopharmacological treatment of depressive disorders.
Dr. Klein is currently directing a longitudinal study of the role of early temperament and emotional style in the development of later mood and anxiety disorders in a large community sample of children. The children were assessed at ages 3 and 6 and are currently being evaluated for the third time at age 9. The study uses multiple measurement strategies to assess potential risk, protective, mediating, and moderating factors in multiple domains, including child emotional reactivity and regulation, executive functioning, psychopathology, psychophysiological and behavioral measures of biases in processing emotional information, susceptibility genes, stress and pubertal hormones, parenting, environmental and family stress, and parental personality and psychopathology. In addition, resting state and task-related functional magnetic resonance imaging (fMRI) measures are being collected on a subset of the larger sample
Dr. Klein is also continuing to work with data sets from several past studies, including several multi-site clinical trials of the treatment of chronically depressed adults; a family and follow-up study of chronically depressed adult outpatients; and a family and follow-up study of a large community sample of adolescents.
Awards and Recognition:
Sustained Mentor Award, Society for Research on Psychopathology, 2012
Award for Distinguished Scientific Contributions to Clinical Psychology, Society of Clinical Psychology (Division 12 of the American Psychological Association), 2012
Ranked 27th in overall productivity and 13th in peer reviewed publications among 1,927 core faculty in accredited Clinical Psychology doctoral programs (Stewart, Wu, & Roberts . Top producers of scholarly publications in Clinical Psychology PhD programs. Journal of Clinical Psychology, 63, 1209-1215).
President, Society for a Science of Clinical Psychology (SSCP) (Section III, Division 12 of the American Psychological Association), 2007
President, Society for Research in Psychopathology (SRP), 2003
Dean’s Award for Excellence in Graduate Mentoring by a Faculty Member, Stony Brook University, 2003
Joseph Zubin Memorial Award, Research Foundation for Mental Hygiene, New York State Psychiatric Institute and Western Psychiatric Institute and Clinic, 2000
Selected Recent Publications:
Hayden, E.P., Klein, D.N., Dougherty, L.R., Olino, T.M., Dyson, M.W., Durbin, C.E., Sheikh, H.I., & Singh, S.M., (2010). The role of brain-derived neurotrophic factor genotype, parental depression, and relationship discord in predicting early-emerging negative emotionality. Psychological Science, 21, 1678-1685.
Klein, D.N. (2010). Chronic depression: Diagnosis and classification. Current Directions in Psychological Science, 19, 96-100.
Olino, T.M., Klein, D.N., Dyson, M.W., Rose, S.A., & Durbin, C.E. (2010). Temperamental emotionality in preschool-aged children and depressive disorders in parents: Associations in a large community sample. Journal of Abnormal Psychology, 119, 468-478.
Bufferd, S.J., Dougherty, L.R., Carlson, G.A., & Klein, D.N. (2011). Parent-reported DSM-IV disorders in a community sample of preschoolers. Comprehensive Psychiatry, 52, 359-369.
Dougherty, L.R., Bufferd, S.J., Carlson, G.A., Dyson, M.W., Olino, T.M., & Klein, D.N. (2011). Preschoolers’ observed temperament and DSM-IV psychiatric disorders assessed with a parent diagnostic interview. Journal of Clinical Child and Adolescent Psychology, 40, 295-306.
Dougherty, L.R., Klein, D.N., Rose, S., & Laptook, R.S. (2011). Hypothalamic-pituitary-adrenal axis reactivity in the preschool-aged offspring of depressed parents: Moderation by early parenting. Psychological Science, 22, 650-658.
Klein, D.N., Kotov, R., & Bufferd, S.J. (2011). Personality and depression: Explanatory models and review of the evidence. Annual Review of Clinical Psychology, 7, 269-295.
Klein, D.N., Leon, A.C., Li, C., D’Zurilla, T.J., Black, S.R., Vivian, D., Dowling, F., Arnow, B.A., Manber, R., Markowitz, J.C., & Kocsis, J.H. (2011). Social problem solving and depressive symptoms over time: A randomized clinical trial comparing Cognitive Behavioral Analysis System of Psychotherapy, Brief Supportive Psychotherapy, and pharmacotherapy. Journal of Consulting and Clinical Psychology, 79, 342-352.
Bufferd, S.J., Dougherty, L.R., Carlson, G.A., Rose, S., & Klein, D.N. (2012). Psychiatric disorders in preschoolers: Continuity from ages 3 to 6. American Journal of Psychiatry, 169, 1157-1164.
Dyson, M.W., Olino. T.M., Durbin, C.E., Goldsmith, H.H., & Klein, D.N. (2012). The structure of temperament in preschoolers: A two-stage factor analytic approach. Emotion, 12, 44-57.
Kim, J., Carlson, G.A., Meyer, S.E., Bufferd, S.J., Dougherty, L.R., Dyson, M.W., Laptook, R.S., Olino, T.M., & Klein, D.N. (2012). Correlates of the CBCL-Dysregulation Profile in preschool-aged children. Journal of Child Psychology and Psychiatry, 53, 918-926.
Klein, D.N., Dyson, M.W., Kujawa, A.J., & Kotov, R. (2012). Temperament and internalizing disorders. In M. Zentner and R. Shiner (Eds.), Handbook of Temperament (pp. 541-561). New York: Guilford Press.
Kujawa, A., Hajcak, G., Torpey, D., Kim, J., & Klein, D. N. (2012). Electrocortical reactivity to emotional faces in young children and associations with maternal and paternal depression. Journal of Child Psychology and Psychiatry, 53, 207-215.
Olino, T.M., Shankman, S.A., Klein, D.N., Seeley, J.R., Pettit, J.W., Farmer, R.F., & Lewinsohn, P.M. (2012). Lifetime rates of psychopathology in single versus multiple diagnostic assessments: Comparison in a community sample of probands and siblings. Journal of Psychiatric Research, 46, 1217-1222.
Smith, H.J., Sheikh, H.I., Dyson, M.W., Olino, T.M., Laptook, R.S., Hayden, E.P., Singh, S.M., & Klein, D.N. (2012). Parenting and child DRD4 genotype interact to predict children’s early emerging effortful control. Child Development, 83, 1932-1944.
Weinberg, A., Klein, D.N., & Hajcak, G. (2012). Increased error-related brain activity distinguishes generalized anxiety disorder with and without comorbid major depressive disorder. Journal of Abnormal Psychology, 121, 885-896.
Rohde, P., Lewinsohn, P.M., Klein, D.N., Seeley, J.R., & Gau, J.M. (2013). Key characteristics of major depressive disorder occurring in childhood, adolescence, emerging adulthood, and adulthood. Clinical Psychological Science, 1, 41-53.
Dougherty, L.R., Smith, V., Olino, T.M., Dyson, M., Bufferd, S., Rose, S., & Klein, D.N. (in press). Maternal depression and early child temperament predict young children’s salivary cortisol three years later. Journal of Abnormal Child Psychology.
Dougherty, L.R., Tolep, M.R., Bufferd, S.J., Olino, T.M., Dyson, M.W., Traditi, J., Rose, S., Carlson, G.A., & Klein, D.N. (in press). Preschool anxiety disorders: Comprehensive assessment of clinical, demographic, temperamental, familial, and life stress correlates. Journal of Clinical Child and Adolescent Psychology.
Hayden, E.P., Olino, T.M., Bufferd, S.J., Miller, A., Dougherty, L.R., Sheikh, H.I., Singh, S.M., & Klein, D.N. (in press). The 5-HTTLPR and BDNF Val66Met polymorphisms and maternal history of depression: Associations with cognitive vulnerability to depression in childhood. Development & Psychopathology.
Klein, D.K., Glenn, C.R., Kosty, D.B., Seeley, J.R., Rohde, P., Lewinsohn, P.M. (in press). Predictors of first lifetime onset of major depressive disorder in young adulthood. Journal of Abnormal Psychology.
Klein, D.N., Kujawa, A.J., Black, S.R., & Pennock, A.T. (in press). Depressive disorders. In T.P. Beauchaine and S.P. Hinshaw (Eds.), Child and adolescent psychopathology, 2nd ed. Hoboken, New Jersey: John Wiley & Sons.
Torpey, D.C., Hajcak, G., Kim, J., Kujawa, A.J., Dyson, M.W., Olino, T.M., & Klein, D.N. (in press). Error-related brain activity in young children: Associations with parental anxiety and child temperamental negative emotionality. Journal of Child Psychology and Psychiatry.
Current Research Support:
National Institute of Mental Health (RO3 MH 097767), “Trajectories of reward sensitivity and depression across adolescence”. 2012-2017. $1,250,000 (direct costs).
Greg Hajcak (Principal Investigator); Daniel Klein (Co-Investigator)
National Institute of Mental Health (RO1 MH 093479) “Personality development and vulnerability to first-episode
depression”. 2012-2017. $1,789,347 (direct costs).
Roman Kotov (Principal Investigator), Daniel Klein, Greg Hajcak (Co-Investigators)
National Institute of Mental Health (RO1 MH 069942), "Temperamental emotionality in preschoolers and depression risk."
2004 - 2014. $4,129,692 (direct costs)
Daniel Klein (Principal Investigator)
National Institute of Mental Health (RO3 MH 094518), “Reward-related brain activity:
Biomarker for risk of depression in childhood” 2011-2013. $100,000 (direct costs).
Greg Hajcak (Principal Investigator); Daniel Klein (Co-Investigator)